Rest in Peace, Containment Priest, Relic of Progenitus, Nihil Spellbomb, and their ilk will shut you down hard, so keeping at least 1 piece of spot removal for these on hand should be a priority
It swam in ancient seas. Attacks Wash Over20 Does 10 damage to 2 of your opponent's Benched Pokmon
Banefire Blaze Bonfire of the Damned Burn from Within Choco-Comet Clan Defiance Crater's Claws Death Grasp Demonfire Devil's Play Disintegrate Electrodominance Energy Bolt Fanning the Flames Flaming Gambit Ghitu Fire Kaervek's Torch Lava Burst Lavalanche Light Up the Night Red Sun's Zenith Titan's Revenge Volcanic Geyser Worldsoul's Rage Zoanthrope You usually need real desperation to add Fall of the Titans to that list, but you could
Landing a Gengar, Pikachu, or Charizard SAR returns multiples of the box cost in a single card
Since its a Trainer card, you can still use a Supporter card during your turn